Stress-induced nitric oxide and adaptive plasticity in conifers

Adaptive plasticity during stress and depression and the role of glutamate-nitric oxide pathways

Introduction The seminal discovery of the antidepressant imipramine in 1958 and of the mood-stabilising actions of lithium ion in 1949 have set the gold standard for research and treatment in mania and depression. However, since these halcyon days of psychopharmacology, drug discovery has not realized its full potential and in many ways is decades behind our understanding of psychiatric illness...

Copper-stress tolerance induced in Phlomis tuberosa depends on nitric oxide accumulation

In this study, we compared the impact of high Cu concentrations on the photosynthetic apparatus and antioxidant capacity of the Phlomis tuberosa. Plants were grown in perlite culture for 5 weeks, and then treated with 0, 100, 200, 300 and 400 µM Cu for 21 days. Results indicated that Phlomis tuberosa plants showed tolerance to 100 and 200 µM Cu. This increased tolerance was achieved through enh...

Nitric oxide and hippocampal synaptic plasticity.

The dependence of NMDA receptor-dependent LTP on postsynaptic depolarization and increases in postsynaptic calcium, coupled with evidence supporting presynaptically mediated increases in transmitter release accompanying LTP, suggest that a retrograde transsynaptic messenger participates in the synaptic enhancement. Although many questions remain unanswered, the available evidence suggests a rol...

Exogenous Nitric oxide (NO) induced oxidative stress and increased production of secondary metabolites in Catharanthus roseus Callus Cells

The objective of the study was to investigate the effect of exogenous nitric oxide on cellular response and production of secondary metabolites in Catharanthus roseus callus. The Cell suspension and callus of C. roseus were treated with sodium nitroprusside, then cell viability, morphology, the amount of H2O2, proline, lipid peroxidation, the activity of superoxide dismutase, catalase and perox...

Nitric Oxide-Induced Polycystic Ovaries in The Wistar Rat